hrp0086p2-p933 | Thyroid P2 | ESPE2016

Clinical Case of Acute Liver Injury in Pediatric Patient with Autoimmune Hyperthyroidism

Caiulo Silvana , Vigone Maria Cristina , Peroni Elena , di Frenna Marianna , Saracco Luca , Memoli Massimo , Barera Graziano , Weber Giovanna

Background: Autoimmune hepatitis (AIH) and methimazole (MMI)-induced toxic hepatitis are both rare diseases in pediatric age.Case presentation: We present the case of a 15-year-old girl affected by idiopathic arthritis and autoimmune thyroiditis. The autoimmune thyroiditis was diagnosed at 13 years of age. At 15 years old she developed hyperthyroidism (TSH <0.01 mcU/ml, FT4 2.3 ng/dl, FT3 8.4 pg/ml, TRAb 18 IU/l) and was treated with MMI (0.28 mg/kg ...